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Worrisome paper about the spike protein's impact on DNA and DNA repair

5 Nov 2021

Image: SARS-CoV-2 Spike protein binding to ACE2 receptor protein on the cell surface 
(ACE2 “receptor,” is the protein that provides the entry point for the coronavirus to hook into and infect a wide range of human cells)



Below is Alex Berenson's commentary on the paper titled SARS-CoV-2 Spike Impairs DNA Damage and Inhibits V(D)J Recombination in Vitro

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This science is at the edge of my ability to understand, much less critique, but the authors are real and at two major Swedish universities. The journal, though not in the top ranks, is real too.

Essentially the authors used a series of complex techniques to look for the full-length coronavirus spike protein - the one the mRNA (and DNA/AAV) vaccines cause your body to produce - inside the nucleus of our cells.

Remember, the reason vaccine fanatics insist that the mRNA vaccines are NOT gene therapies is that they supposedly have no impact on the nucleus of the cell, where we store our DNA, our core genetic material. Instead, the mRNA is degraded in the cytosol, which is outside the cell’s nucleus.

Some scientists have argued that under certain unlikely circumstances the mRNA can make its way into the nucleus - but that debate is actually irrelevant here. The authors were looking not for the vaccine material but for the presence of the coronavirus proteins, including the spike, in the nucleus.

And - to their surprise - they found the spike.

They then went on to examine how the spike protein might impact the repair of damaged DNA in the nucleus.

Over time, radiation, chemicals, and other molecular-level insults can introduce errors into our DNA, which can cause a cascade of catastrophic consequences, including cancer. To prevent this, our cells have mechanisms to repair their own DNA.

But - at least in the experiments these two scientists ran - the spike protein appeared to interfere with our own DNA repair proteins: “Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA damage repair by impeding key DNA repair protein BRCA1 and 53BP1 recruitment to the damage site.”

To be clear, the scientists did NOT prove the spike protein was causing these problems in people, or even animals. Nor did they show they had found the spike protein in human nuclei following the administration of Covid vaccines. Their research was confined to cells - in vitro, not in vivo.

Nonetheless, at a time when advanced countries that have high mRNA (and DNA/AAV) vaccination rates are seeing unusually full hospitals and higher-than-normal death rates, they are yet more cause for concern. As the authors explained:

“Our findings reveal a potential molecular mechanism by which the spike protein might impede adaptive immunity and underscore the potential side effects of full-length spike-based vaccines.”

(Image Credit: Kateryna Kon/ Shutterstock)

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